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Intravitreal bevacizumab for exudative retinal detachment post laser therapy for retinopathy of prematurity
1Department of Ophthalmology, University of Alberta, Edmonton Alberta.
Insights
Retinopathy of prematurity (ROP) can cause retinal detachment after laser therapy. Intravitreal bevacizumab injections effectively treated exudative retinal detachments in two infants with ROP.
Area of Science:
- Ophthalmology
- Neonatology
- Pediatric Medicine
Background:
- Retinopathy of prematurity (ROP) is a significant cause of childhood blindness, primarily affecting premature infants.
- While often self-limiting, some ROP cases can lead to retinal detachment, even after treatment.
- Exudative retinal detachments are rare but documented complications following conventional laser therapy for ROP.
Observation:
- This study presents two cases of exudative retinal detachment.
- These detachments occurred subsequent to laser therapy for prethreshold and threshold ROP.
- The patients were premature infants diagnosed with ROP.
Findings:
- Both cases of exudative retinal detachment showed a positive response to treatment.
- A series of intravitreal bevacizumab injections were administered to the affected infants.
- The treatment led to favorable outcomes in managing the retinal detachments.
Implications:
- Intravitreal bevacizumab may be a viable treatment option for exudative retinal detachment post-ROP laser therapy.
- This finding could offer a new therapeutic avenue for a rare but serious complication of ROP treatment.
- Further research is warranted to confirm the efficacy and safety of bevacizumab in such cases.
Abstract:
Retinopathy of prematurity (ROP), a leading cause of pediatric blindness, predominantly affects premature and low-birth-weight infants. Although many cases are self-limiting, a minority progress to retinal detachment despite treatment. Exudative retinal detachments, although uncommon, have been reported after conventional laser therapy.(1-3) We report 2 cases of exudative retinal detachment after laser therapy for prethreshold and threshold ROP that responded favourably to a series of intravitreal bevacizumab injections.
