Related Experiment Video
Updated: Apr 30, 2026

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
Pyoderma gangrenosum successfully treated with antiretroviral therapy alone in a human immunodeficiency
Naoya Sakamoto1, Naoki Yanagisawa2, Noritaka Sekiya3
1Department of Infectious Diseases, Tokyo Metropolitan Komagome Hospital, Japan; Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, Japan.
Abstract:
We report a case of a 60-year-old man infected with human immunodeficiency virus (HIV) who was transferred to our hospital for management of multiple non-healing, painful ulcers on the lower extremities. The histological findings of the biopsy specimen were compatible with the diagnosis of pyoderma gangrenosum (PG). An association between HIV infection and the development of PG was considered after a thorough investigation. Antiretroviral therapy without the use of adjunctive immunosuppressive agents resulted in clinical improvement. Our case implies that antiretroviral therapy alone could heal PG in untreated HIV-infected patients.
More Related Videos
Related Concept Videos
Retrovirus Life Cycles
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Sexually Transmitted Infections

