Related Experiment Video
Updated: Apr 30, 2026

05:16
Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models
Published on: October 27, 2023
2.0K
Traumatized immature teeth treated with 2 protocols of pulp revascularization
Juliana Yuri Nagata1, Brenda Paula Figueiredo de Almeida Gomes1, Thiago Farias Rocha Lima1
1Department of Restorative Dentistry, Endodontics Area, State University of Campinas-UNICAMP, Piracicaba, São Paulo, Brazil.
Journal of Endodontics
|April 29, 2014
Summary
Pulp revascularization using triple antibiotic paste (TAP) or calcium hydroxide and chlorhexidine gel (CHP) showed similar clinical and radiographic outcomes for traumatized immature teeth. However, TAP caused significant tooth discoloration, making CHP a more esthetic option.
Area of Science:
- Endodontics
- Pediatric Dentistry
- Dental Traumatology
Background:
- Pulp revascularization is a viable treatment for immature necrotic teeth following trauma.
- Evaluating different revascularization protocols is crucial for optimizing outcomes.
Purpose of the Study:
- To compare the clinical and radiographic effectiveness of two pulp revascularization protocols in traumatized immature teeth.
- To assess the outcomes of triple antibiotic paste (TAP) versus calcium hydroxide and chlorhexidine gel (CHP).
Main Methods:
- Twenty-three necrotic immature incisors in patients aged 7-17 were treated with either TAP (n=12) or CHP (n=11).
- Clinical and radiographic evaluations were performed over a 9-19 month follow-up period.
Main Results:
- Both TAP and CHP groups showed significant pain reduction and radiographic signs of healing, including periapical repair and apical closure.
- TAP treatment resulted in significantly higher rates of crown discoloration (83.3%) compared to CHP.
- Root lengthening and dentinal wall thickening were observed in both groups, with slightly higher incidence in the TAP group.
Conclusions:
- Pulp revascularization with TAP and CHP yields comparable clinical and radiographic results for traumatized immature teeth.
- Triple antibiotic paste (TAP) is associated with a significant esthetic disadvantage due to tooth discoloration.
- Calcium hydroxide and chlorhexidine gel (CHP) may be preferred when esthetics are a primary concern.

