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Related Experiment Videos

The effect of electrode configuration on the unipolar His-bundle electrogram.

A H Kadish1, F Morady, S Rosenheck

  • 1Division of Cardiology, University of Michigan Medical Center, Ann Arbor.

Pacing and Clinical Electrophysiology : PACE
|September 1, 1989
PubMed
Summary

Recording unipolar electrograms from the His bundle position is optimized using an inferior vena cava anode for a better signal-to-noise ratio. This method improves His bundle ablation catheter positioning during electrophysiology studies.

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Area of Science:

  • Electrophysiology
  • Cardiac Electrophysiology
  • Medical Device Technology

Background:

  • Standardization of unipolar electrogram recording techniques for His bundle ablation is lacking.
  • Current methods for recording His bundle electrograms may not be optimal for catheter positioning.

Purpose of the Study:

  • To evaluate the impact of different anode locations on unipolar electrograms recorded from the His bundle position.
  • To determine the optimal filter settings and anode configuration for recording His bundle electrograms.

Main Methods:

  • Ten patients undergoing electrophysiology studies had unipolar atrial, His bundle, and ventricular electrograms recorded.
  • Five anode locations (chest wall variations, inferior vena cava) and two filter settings (50-500 Hz, 0.05-1000 Hz) were tested.

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  • Signal amplitude, duration, and morphology were analyzed, along with signal-to-noise ratio.

    • Main Results:

    • Anode location did not consistently affect electrogram amplitude, duration, or morphology.
    • The inferior vena cava anode yielded the highest signal-to-noise ratio compared to chest wall anodes.
    • A 50-500 Hz filter setting significantly decreased electrogram amplitudes compared to a 0.05-1000 Hz setting.

    Conclusions:

    • Using an electrode catheter in the inferior vena cava as the anode provides a superior signal-to-noise ratio for unipolar electrograms from the His bundle position.
    • This technique is optimal for recording unipolar electrograms, enhancing accuracy in His bundle ablation procedures.