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Rhinovirus and the developing lung

D W Cox1, P N Le Souëf2

  • 1School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia; Respiratory Department, Our Lady's Children's Hospital, Crumlin, Dublin 12, Ireland.

Paediatric Respiratory Reviews
|April 29, 2014
PubMed

Insights

Human rhinovirus (HRV) is the most frequent cause of childhood respiratory illnesses. This review explores the connection between HRV infections and long-term lower airway disorders in children.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Respiratory Medicine

Background:

  • Human rhinovirus (HRV) is the most common cause of acute respiratory illnesses (ARIs) in children.
  • Advanced PCR techniques confirm HRV as a primary agent in childhood ARIs like bronchiolitis, asthma, pneumonia, and croup.

Purpose of the Study:

  • To review the relationship between HRV infections and childhood lower airway disorders.
  • To investigate the less understood long-term implications of HRV infections.

Main Methods:

  • Literature review of studies on HRV and childhood respiratory conditions.
  • Analysis of PCR-confirmed HRV cases and associated lower airway diseases.

Main Results:

  • HRV identified as a leading cause of various ARIs in children.
  • Evidence suggests a potential link between HRV and persistent lower airway issues, though long-term effects require further study.

Conclusions:

  • HRV is a significant pathogen in pediatric respiratory infections.
  • Further research is needed to fully elucidate the long-term consequences of HRV on children's lower airways.

Keywords:
Rhinoviruschildrenrespiratory illnesses

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