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Published on: November 19, 2014
Lack of effect of risperidone or olanzapine dose reduction on subjective experiences in stable patients with
Hiroyoshi Takeuchi1, Takefumi Suzuki2, Gary Remington3
1Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan; Schizophrenia Division, Complex Mental Illness Program, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8.
Abstract:
Sixty-one patients with schizophrenia stably treated with risperidone or olanzapine were randomly assigned to dose-reduction-by-half group or dose maintenance group. Subjective experiences were assessed at baseline and 28 weeks using three different self-rating scales. No significant differences in changes of subjective experiences were observed between the two groups.
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