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Electrospinning of polymeric nanofibers for drug delivery applications

Xiuli Hu1, Shi Liu2, Guangyuan Zhou3

  • 1State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.

Journal of Controlled Release : Official Journal of the Controlled Release Society
|April 29, 2014
PubMed

Keywords:
Drug deliveryElectrospinningLocal chemotherapyWound dressing

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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