[Immunologic status of patients in the late period after cranio-cerebral trauma]

Immune disorders characteristic of the late period of craniocerebral trauma involve T-cellular, regulatory link and were represented by a reduction of T-cells count and function with disbalance in lymphocytes-helpers, increase in macrophagal and lymphoid suppressors activity susceptible to indomethacin++. The changes also include the neurosensibilization of cellular and humoral type to brain-specific++ proteins: OBM, 14-3-2, S-100. Most pronounced changes were detected in patients after severe brain concussion with focal neural changes persisting in the late period.