Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Errors in Germline Biomarker Testing: Significant Consequences and Missed Opportunities for Cancer Control in Patients and Their Families.

Cancer journal (Sudbury, Mass.)·2026
Same author

Hot Flashes: Clinical Summary of the ONS Guidelines™ for Cancer Treatment-Related Hot Flashes in Women With Breast Cancer and Men With Prostate Cancer.

Clinical journal of oncology nursing·2020
Same author

ONS Guidelines™ for Cancer Treatment-Related Hot Flashes in Women With Breast Cancer and Men With Prostate Cancer.

Oncology nursing forum·2020
Same author

Telegenetics: Remote Counseling During the COVID-19 Pandemic.

Clinical journal of oncology nursing·2020
Same author

Genetic Service Delivery Models: Exploring Approaches to Care for Families With Hereditary Cancer Risk

Clinical journal of oncology nursing·2019
Same author

Response to "Male Patients With Breast Cancer: Addressing Needs Using an Educational Task Force"

Clinical journal of oncology nursing·2018

Related Experiment Video

Updated: Apr 30, 2026

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

6.5K

Microsatellite testing in colon cancer

Suzanne M Mahon1

  • 1Department of Internal Medicine and in the School of Nursing, Saint Louis University in Missouri.

Oncology Nursing Forum
|April 29, 2014
PubMed
Summary
This summary is machine-generated.

Understanding the molecular genetic basis of colorectal cancer (CRC) aids in identifying hereditary cancer syndromes like Lynch syndrome. This knowledge is crucial for targeted therapies and clinical practice integration.

Keywords:
colorectal cancermolecular pathwaysmolecular testing

More Related Videos

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
08:12

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer

Published on: March 14, 2019

5.1K
Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing
15:17

Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing

Published on: September 25, 2011

13.4K

Related Experiment Videos

Last Updated: Apr 30, 2026

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

6.5K
Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
08:12

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer

Published on: March 14, 2019

5.1K
Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing
15:17

Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing

Published on: September 25, 2011

13.4K

Area of Science:

  • Oncology
  • Molecular Genetics
  • Cancer Research

Background:

  • Significant advancements in understanding the molecular genetic basis of colorectal cancer (CRC) are occurring.
  • This knowledge is foundational for deciphering the genetic underpinnings of other tumor types.
  • Oncology nurses must prepare for the routine incorporation of molecular information and testing in clinical settings.

Purpose of the Study:

  • To highlight the importance of molecular genetic understanding in colorectal cancer (CRC).
  • To emphasize the role of molecular testing in identifying hereditary cancer syndromes, such as Lynch syndrome.
  • To underscore the value of genetic insights in guiding targeted therapy selection for CRC patients.

Main Methods:

  • Review of current research on the molecular genetics of colorectal cancer.
  • Analysis of the implications of molecular profiling for clinical practice.
  • Discussion of the connection between genetic knowledge and targeted treatment strategies.

Main Results:

  • Molecular genetic insights are advancing the understanding of CRC.
  • Molecular testing facilitates the identification of at-risk families for hereditary syndromes like Lynch syndrome.
  • Genetic information is vital for selecting effective targeted therapies.

Conclusions:

  • The molecular genetic landscape of colorectal cancer is increasingly understood.
  • Routine molecular testing in CRC is essential for identifying hereditary risks and guiding treatment.
  • Knowledge of CRC's genetic basis is critical for personalized oncology and effective targeted therapy selection.