Related Experiment Video
Updated: Apr 30, 2026

09:59
A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
Published on: September 16, 2017
16.7K
Optimization of inversion time for postmortem short-tau inversion recovery (STIR) MR imaging
Tomoya Kobayashi1, Masahiko Monma, Takeshi Baba
1Department of Radiological Technology, Tsukuba Medical Center Hospital.
Summary
Postmortem MRI fat suppression is improved by optimizing inversion time (TI) based on the linear correlation between subcutaneous fat T1 values and body temperature. This enhances image quality in postmortem magnetic resonance (PMMR) imaging.
Area of Science:
- Radiology
- Medical Imaging
- Forensic Science
Background:
- Postmortem magnetic resonance (PMMR) imaging presents challenges in signal intensity and contrast compared to in-vivo imaging.
- Achieving adequate fat suppression is crucial for accurate interpretation of PMMR scans.
Purpose of the Study:
- To optimize inversion time (TI) for short-tau inversion recovery (STIR) PMMR imaging to achieve sufficient fat suppression.
- To investigate the relationship between subcutaneous fat T1 values and postmortem body temperature.
Main Methods:
- 37 deceased adult patients underwent 1.5 tesla PMMR imaging.
- Subcutaneous fat T1 values were measured and correlated with rectal temperature (RT) using Pearson's correlation coefficient.
- STIR images were acquired using both standard and optimized TI values.
Main Results:
- A strong positive correlation (r = 0.91, P < 0.0001) was found between subcutaneous fat T1 values and RT.
- The regression equation T1 = 2.6*RT + 90 was established for 1.5T.
- Optimized TI significantly improved subcutaneous fat signal suppression.
Conclusions:
- Subcutaneous fat T1 values in PMMR exhibit a linear correlation with body temperature.
- This correlation enables easy optimization of TI for improved fat suppression in PMMR STIR imaging.

