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Graves' disease as an uncommon cause of acute pericarditis

Kirsten A Kortekaas, Kirsten Kortekaas1, Bas van der Lienden

  • 1Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.

BMJ Case Reports
|April 29, 2014
PubMed

Insights

Acute pericarditis, an inflammation of the heart lining, can be an uncommon complication of Graves' disease. Prompt treatment combining anti-inflammatory drugs and hyperthyroidism management is crucial for better outcomes.

Area of Science:

  • Cardiology
  • Endocrinology

Background:

  • Acute pericarditis presents in dry, fibrinous, or effusive forms, irrespective of the underlying cause.
  • Graves' disease, an autoimmune thyroid disorder, can rarely lead to cardiac complications like pericarditis.

Observation:

  • A case study of a 44-year-old man with acute pericarditis is presented.
  • The pericarditis was linked to an exacerbation of Graves' disease, stemming from treatment non-compliance.

Findings:

  • Pericarditis is an infrequent cardiac manifestation of Graves' disease.
  • Undetected or poorly managed pericarditis in Graves' disease patients is associated with increased recurrence rates.

Implications:

  • Effective management requires a dual approach: anti-inflammatory medications for pericarditis and treatment for hyperthyroidism.
  • Further research is needed to clarify the precise pathophysiological mechanisms connecting Graves' disease and pericarditis.

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