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Updated: Apr 30, 2026

Protocol for Dengue Infections in Mosquitoes A. aegypti and Infection Phenotype Determination
Published on: July 4, 2007
A stuctured discrete model for dengue fever infections and the determination of R0 from age-stratified serological
Renato Francisco Lopes Mello1, César Castilho
1Departamento de Matemática (IMECC), Universidade Estadual de Campinas (UNICAMP), Campinas, SP, CEP 13083-859, Brazil.
Abstract:
A time discrete age-structured model for modeling the spread of Dengue fever is built. The demographic dynamics is introduced trough the Leslie model. The basic reproductive number is introduced, and an approximation for it is built. The final age distributions for the susceptibles, infected and removed are obtained, and we show how they can be used to produce an actual estimate for R0 from stratified serological data. An application is made using data from Recife, Brazil, and explicit estimates for R0 are given.
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