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Hypertensive Disorders of Pregnancy - A Life-Long Risk?!
C E Schausberger1, V R Jacobs1, G Bogner1
1Universitätsklinik für Frauenheilkunde und Geburtshilfe (OB/GYN) der Salzburger Landesklinken (SALK) , & Paracelsus Medizinische Universität (PMU).
Insights
Hypertensive disorders during pregnancy significantly increase the long-term risk of developing hypertension and cardiovascular diseases. Early detection and management of hypertension post-pregnancy are crucial for preventing future health complications.
Area of Science:
- Cardiology
- Obstetrics
- Public Health
Background:
- Arterial hypertension is a leading cause of cardiovascular disease (CVD) deaths globally.
- Hypertensive disorders of pregnancy (HDP) are major contributors to maternal and fetal morbidity and mortality.
- HDP is a significant risk factor for developing hypertension and subsequent CVD later in life.
Purpose of the Study:
- To elucidate the association between hypertensive disorders of pregnancy and the subsequent development of cardiovascular diseases.
- To highlight the increased cardiovascular risks following hypertensive disorders of pregnancy.
Main Methods:
- A specific and selective literature research was conducted.
- Analysis of relative risks for cardiovascular outcomes post-HDP.
Main Results:
- HDP significantly elevates risks: hypertension (3.7x), ischemic heart disease (2.2x), cerebral insult (1.8x), and cardiovascular mortality (1.5x).
- A substantial knowledge gap exists among medical specialists regarding HDP's link to ischemic heart disease, stroke, and reduced life expectancy.
- Many patients with post-HDP hypertension are undiagnosed or undertreated, with only 28-38% receiving appropriate therapy.
Conclusions:
- Comprehensive follow-up and early hypertension management after HDP are essential for preventing long-term cardiovascular complications.
- General practitioners, internists, and gynecologists share a critical responsibility in mitigating these late-occurring cardiovascular risks.
Abstract:
Background: Arterial hypertension is one of the most important causes of cardiovascular diseases, and the latter are responsible for almost half of the deaths in the industrialised nations. Hypertensive disorders of pregnancy constitute one of the most frequent causes of feto-maternal morbidity and mortality; on the other hand the occurrence of a hypertensive disorder of pregnancy represents a risk for the later development of hypertension and the cardiovascular risks resulting therefrom. The aim of this article is to demonstrate the association of hypertensive disorders of pregnancy with consecutive cardiovascular diseases. Materials and Methods: Specific selective literature research. Results: After the occurrence of a hypertensive disorder of pregnancy the relative risks for hypertension are 3.7 (2.70-5.05), for ischaemic heart disease 2.2 (1.86-2.52), for cerebral insult 1.8 (1.45-2.27) and for mortality resulting from cardiovascular causes 1.5 (1.05-2.14) and are thus significant. According to a recent study 56 % of internal specialists and 23 % of gynecologists do not know about the association of preeclampsia with ischemic heart disease, 48 % and 38 % respectively are not aware of the link with stroke and 79 % and 77 % respectively are not aware of the association with a reduced life expectancy after preeclampsia. The presence of hypertension is not known by many of the patients, merely 28-38 % receive an appropriate therapy. Conclusion: Adequate follow-up after hypertensive disorders of pregnancy and the early recognition of and therapy for hypertension represent the cornerstones in the prevention of late cardiovascular sequelae. General practitioners, specialist for internal medicine and gynaecologists have a special responsibility with regard to the reduction of later complications.
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