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Related Concept Videos

Esophageal Achalasia01:27

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Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide...
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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Gastroesophageal Reflux Disease01:25

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Gastroesophageal reflux disease (GERD) is the backward flow of stomach contents (acid, pepsin, or bile) into the esophagus, causing mucosal inflammation known as esophagitis. It results from failure of antireflux mechanisms, mainly the lower esophageal sphincter (LES), influenced by mechanical and physiological factors.Etiology and Risk FactorsGERD develops when LES function is weakened or when intra-abdominal pressure increases. Risk factors include aging, obesity, and sliding hiatal hernia,...
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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Related Experiment Video

Updated: Apr 30, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
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Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

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Dysphagia in the elderly.

Muhammad Aslam1, Michael F Vaezi1

  • 1Dr Aslam is a research assistant professor and Dr Vaezi is a professor of medicine in the Division of Gastroenterology, Hepatology, and Nutrition at Vanderbilt University Medical Center in Nashville, Tennessee.

Gastroenterology & Hepatology
|April 29, 2014
PubMed
Summary
This summary is machine-generated.

Elderly patients often experience dysphagia due to health issues. Swallowing tests and rehabilitation can help manage this common condition in older adults.

Keywords:
Esophageal dysphagiaagingfiberoptic endoscopic evaluation of swallowingoropharyngeal dysphagiaswallow functionvideofluoroscopic swallowing study

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Related Experiment Videos

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Area of Science:

  • Gerontology
  • Gastroenterology
  • Neurology

Background:

  • Aging populations face increased dysphagia prevalence.
  • Comorbidities like obesity and GERD exacerbate swallowing difficulties in the elderly.
  • Healthcare providers frequently encounter older adults with oropharyngeal or esophageal dysphagia.

Purpose of the Study:

  • To outline the challenges of dysphagia in elderly patients.
  • To describe diagnostic methods for dysphagia.
  • To introduce swallow rehabilitation as a therapeutic approach.

Main Methods:

  • Review of diagnostic tools for dysphagia.
  • Discussion of videofluoroscopic swallowing study (VFSS).
  • Explanation of fiberoptic endoscopic evaluation of swallowing (FEES).

Main Results:

  • Dysphagia is common in elderly patients, often linked to underlying health conditions.
  • VFSS and FEES are effective diagnostic modalities.
  • Swallow rehabilitation aids in compensation and neuromuscular strengthening.

Conclusions:

  • Dysphagia management in the elderly requires understanding of associated health conditions.
  • Appropriate diagnostic testing is crucial for accurate assessment.
  • Swallow rehabilitation offers a viable strategy for improving swallowing function and patient outcomes.