Advances in remineralization for early carious lesions: a comprehensive review

A greater understanding of the dental caries process and improved and more diverse methodologies to assess early demineralization and caries has enabled development of a new class of remineralizing therapeutics. Hence, an emerging goal of modern dentistry is to manage non-cavitated carious lesions non-invasively through remineralization in an effort to prevent disease progression and improve strength, esthetics, and function of teeth. A critical element fundamental to this current therapeutic philosophy is the need for new and highly efficacious technologies for enamel remineralization. The aim of this article is to provide an overview of new compositions and to review contemporary nonfluoridated systems in terms of their basic composition, mode of delivery, and currently available evidence.