Blood pressure variability and morning blood pressure surge in elderly Chinese hypertensive patients
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Published on: May 3, 2018
Xiaobo Qin1, Qin Zhang, Suping Yang
1Department of Electrocardiography, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Insights
Elderly hypertensive patients show increased blood pressure variability and morning systolic blood pressure surge. These surges are linked to body mass index, smoking history, and circadian blood pressure patterns.
Area of Science:
- Cardiology
- Gerontology
- Hypertension Research
Background:
- Blood pressure variability (BPV) and morning systolic blood pressure surge (MBPS) are critical indicators of cardiovascular risk.
- Understanding age-related differences in BPV and MBPS is essential for managing hypertension in diverse populations.
Purpose of the Study:
- To investigate blood pressure variability (BPV) and morning systolic blood pressure surge (MBPS) in elderly versus younger hypertensive Chinese patients.
- To identify factors associated with MBPS in these patient groups.
Main Methods:
- Retrospective analysis of ambulatory blood pressure monitoring (ABPM) data from 513 elderly and 188 younger hypertensive patients.
- Statistical analysis including multiple linear regression to identify associated factors.
Main Results:
- Elderly hypertensive patients exhibited significantly higher BPV compared to younger patients.
- The 80 years and older group showed a notable increase in BPV.
- MBPS was lower in younger patients than in elderly patients, peaking in the 75-79 age group.
- Factors associated with MBPS included body mass index (BMI), smoking history (up to 50 years), and circadian blood pressure variation.
Conclusions:
- Systolic BPV and MBPS are elevated in elderly Chinese hypertensive patients.
- MBPS is significantly associated with BMI, smoking duration, and circadian blood pressure patterns in hypertensive individuals.
Abstract:
This retrospective study aimed to investigate blood pressure variability (BPV), morning systolic blood pressure surge (MBPS), and the associated factors in 513 elderly (65 years and older) and 188 younger (younger than 65 years) hypertensive Chinese patients who had ambulatory blood pressure monitoring (ABPM) at our hospital from January 1, 2002, to December 31, 2010. The MBPS was lower in the younger patients compared with the elderly patients, and it was highest in the 75 years and older and younger than 80 group (29.0±13.4 mm Hg). Compared with other groups, the 80 years and older group had a significant increase in BPV (P<.05). Multiple linear regression analysis showed that body mass index (BMI; P<.01), up to 50 years of smoking (P≤.03), and circadian blood pressure variation (P<.01) were factors associated with MPBS. In summary, systolic BPV and MBPS were increased in elderly Chinese hypertensive patients, and the MBPS was associated with BMI, years of smoking, and circadian blood pressure variation.
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