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Published on: July 31, 2016
Percutaneous balloon pericardiotomy as the initial and definitive treatment for malignant pericardial effusion
Juan Ruiz-García1, Santiago Jiménez-Valero1, Raúl Moreno1
1Servicio de Cardiología, Hospital Universitario La Paz, Madrid, Spain.
Insights
Percutaneous balloon pericardiotomy offers an effective and safe initial treatment for malignant pericardial effusion, reducing recurrence rates compared to pericardiocentesis alone.
Area of Science:
- Cardiology
- Oncology
- Interventional Radiology
Background:
- Malignant pericardial effusion frequently recurs after pericardiocentesis.
- Patients with advanced cancer often experience hemodynamic compromise due to effusions.
Purpose of the Study:
- To evaluate percutaneous balloon pericardiotomy (PBP) as a primary treatment for malignant pericardial effusion.
- To assess the safety and efficacy of PBP in preventing effusion recurrence.
Main Methods:
- Retrospective analysis of 17 PBPs in 16 patients with advanced cancer.
- Inclusion criteria: severe circumferential effusion, hemodynamic compromise.
- Data collected: clinical, echocardiographic, and follow-up characteristics.
Main Results:
- All 17 procedures were successful, well-tolerated, and without acute complications.
- No infectious complications occurred during follow-up (median 44 days).
- Only 3 patients required repeat procedures (2 pericardial windows, 1 repeat PBP).
Conclusions:
- Percutaneous balloon pericardiotomy is a simple, safe, and effective initial treatment for malignant pericardial effusion.
- PBP can prevent recurrence and avoid more invasive procedures in cancer patients.
- This technique is particularly beneficial for patients with severe effusions and hemodynamic compromise.
Introduction And Objectives:
Malignant pericardial effusion has a high recurrence rate after pericardiocentesis. We sought to confirm the efficacy of percutaneous balloon pericardiotomy as the initial treatment of choice for these effusions.
Methods:
Retrospective analysis of the clinical, echocardiographic, and follow-up characteristics of a consecutive series of percutaneous balloon pericardiotomies carried out in a single center in patients with advanced cancer.
Results:
Seventeen percutaneous balloon pericardiotomies were performed in 16 patients with a mean age of 66.2 (15.2) years. Fourteen patients had pathologically confirmed metastatic neoplastic disease, 3 had previously required pericardiocentesis, and in the remaining patients percutaneous balloon pericardiotomy was the first treatment for the effusion. All patients had a severe circumferential effusion, and most presented evidence of hemodynamic compromise on echocardiography. In all cases, the procedure was successful, there were no acute complications, and it was well tolerated at the first attempt. There were no infectious complications during follow-up (median, 44 [interquartile range, 36-225] days). One patient developed a large pleural effusion that did not require treatment. Three patients needed a new pericardial procedure: 2 had elective pericardial window surgeries and 1 had a second percutaneous balloon pericardiotomy.
Conclusions:
Percutaneous balloon pericardiotomy is a simple, safe technique that can be effective in the prevention of recurrence in many patients with severe malignant pericardial effusion. The characteristics of this procedure make it particularly useful in this group of patients to avoid more aggressive, poorly tolerated approaches.
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