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Updated: Apr 30, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
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Heminasal agenesis: a reconstructive challenge.

Mark Fisher1, Jonathan Zelken, Richard J Redett

  • 1From the Departments of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

The Journal of Craniofacial Surgery
|April 30, 2014
PubMed
Summary
This summary is machine-generated.

Heminasal agenesis, a rare congenital defect, presents reconstruction challenges. This case details a 5-year-old girl

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Area of Science:

  • Plastic Surgery
  • Craniofacial Surgery
  • Congenital Malformations

Background:

  • Heminasal agenesis is a rare congenital anomaly impacting facial development.
  • Reconstruction is complex due to missing anatomical structures like lining, cartilage, and skin.
  • Associated anomalies often include ocular, lacrimal, and midfacial deformities.

Observation:

  • A 5-year-old girl presented with heminasal agenesis.
  • She also had hypertelorism, eyelid coloboma, and maxillary hypoplasia.
  • A multidisciplinary approach was employed for reconstruction.

Findings:

  • Facial bipartition corrected hypertelorism, with a cantilever bone graft used.
  • A forehead flap, modeled from a twin sister, was utilized for reconstruction.
  • Conchal and rib cartilage provided alar and dorsal support.

Implications:

  • This case highlights a successful reconstructive strategy for complex heminasal agenesis.
  • It underscores the importance of tailored surgical planning for craniofacial anomalies.
  • The study contributes to understanding reconstructive options for rare congenital defects.