Related Experiment Video
Updated: Apr 30, 2026

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
Risk factors for 'small for gestational age babies'
T Ruwanpathirana1, D N Fernando
1Family Health Bureau, Ministry of Health, Colombo, Sri Lanka, thilangar@yahoo.com.
Insights
Seven key risk factors for small for gestational age (SGA) babies were identified, including low pre-pregnancy weight and high stress levels. These findings can guide interventions to improve birth outcomes for newborns.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Health
- Maternal-Fetal Medicine
Background:
- Small for gestational age (SGA) newborns are at increased risk for adverse health outcomes.
- Identifying modifiable risk factors is crucial for developing effective prevention strategies.
Purpose of the Study:
- To determine the significant risk factors associated with the development of small for gestational age (SGA) babies.
Main Methods:
- A nested case-control study was conducted in Colombo district, Sri Lanka.
- SGA was defined as birth weight below the 10th percentile using Sri Lankan-specific growth curves.
- Data were collected from 1,200 pregnant women, with 167 cases and 668 controls.
Main Results:
- Multivariate analysis revealed seven significant risk factors for SGA.
- These include nulliparity, inadequate gestational weight gain, high physical activity, low pre-pregnancy maternal weight (<38 kg), high stress in the second trimester, pregnancy-induced hypertension (PIH), and insufficient husband support.
Conclusions:
- The identified risk factors provide critical insights for targeted intervention programs.
- Interventions focusing on maternal nutrition, stress reduction, and social support may help reduce the incidence of SGA births.
Objective:
To identify the risk factors for small for gestational age (SGA) babies.
Methods:
The present study was a nested case control study which was carried out by two Medical Officers of Health areas (The field level administrative unit responsible for provision of preventive and promotive health services) in Colombo district. SGA babies were identified using 'weight for gestational age' curves developed for Sri Lankan babies. Newborns of 1,200 pregnant women, who were identified within the first 8 wk of amenorrhea and who delivered in selected hospitals were included in the study. Sample size was calculated as n=167 cases and 4 n=668 controls, with four controls for each case. A case was defined as a newborn whose birth weight was less than the 10th percentile of the weight for gestational age, the control being a newborn whose birth weight was between the 10th and the 90th percentile of the weight for gestational age.
Results:
Multivariate analysis identified 7 significant risk factors as, number of live born children=0, inadequate weight gain during pregnancy according to initial BMI, maximum and minimum physical work, mother's pre-pregnant weight less than 38 kg, high level of stress at second trimester, presence of pregnancy induced hypertension (PIH) and inadequate support from husband.
Conclusion:
The risk factors indicate the directions for planning intervention programs.
Related Concept Videos
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Teratogenicity
Development of the Oral Microbiota
Diabetes Mellitus: Type 2 and Gestational
Development of Human Microbiota
Factors Affecting Drug Response: Overview

