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[Benign prostatic hypertrophy. Treatment using local hyperthermia].

M Zerbib1, A Steg, S Conquy

  • 1Clinique urologique, Hôpital Cochin, Paris.

Presse Medicale (Paris, France : 1983)
|September 16, 1989
PubMed
Summary
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Local microwave hyperthermia offers a non-surgical treatment option for benign prostatic hypertrophy (BPH). This outpatient procedure showed objective improvement in 45% and subjective improvement in 58% of patients.

Area of Science:

  • Urology
  • Medical Devices
  • Oncology

Context:

  • Benign prostatic hypertrophy (BPH) significantly impacts quality of life, often necessitating invasive treatments.
  • Current BPH treatments may have undesirable side effects, such as retrograde ejaculation.
  • Identifying minimally invasive and effective BPH therapies is crucial.

Purpose:

  • To evaluate the efficacy and safety of local microwave hyperthermia for treating benign prostatic hypertrophy (BPH).
  • To assess objective and subjective improvements in patients with severe voiding symptoms due to BPH.
  • To determine the suitability of hyperthermia for specific patient populations, including those with contraindications for surgery.

Summary:

  • Forty-three male patients (57-81 years) with severe BPH symptoms underwent 5 weekly 60-minute outpatient sessions of microwave hyperthermia (42.5-43.5°C) via a rectal probe.

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  • Objective improvements (post-voiding residual volume, flow rate) were noted in 45% of patients, while subjective improvements (frequency, urgency, nocturia) were observed in 58%.
  • Catheter removal was possible in 4 out of 5 long-term catheterized patients, suggesting potential for improved bladder function.

    • Impact:

    • Local hyperthermia presents a promising, minimally invasive treatment alternative for benign prostatic hypertrophy (BPH).
    • The procedure is particularly suitable for patients who wish to avoid surgical side effects like retrograde ejaculation or are poor surgical candidates.
    • Further research is warranted to validate these findings and establish hyperthermia as a standard BPH treatment.