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Incidence and paris classification of pediatric inflammatory bowel disease
Katalin Eszter Müller1, Peter Laszlo Lakatos2, Maria Papp3
11st Department of Pediatrics, Semmelweis University, 53 Bókay Street, Budapest 1083, Hungary.
Insights
Pediatric inflammatory bowel disease (IBD) incidence is rising globally. The Paris Classification aids in understanding IBD phenotypes, crucial for managing this growing health challenge.
Area of Science:
- Gastroenterology
- Epidemiology
- Pediatrics
Background:
- Rising incidence of inflammatory bowel disease (IBD) presents a growing healthcare burden.
- Clinical variability in IBD necessitates better characterization for predicting outcomes.
Purpose of the Study:
- To review current incidence trends of pediatric IBD.
- To evaluate the utility of the Paris Classification in defining pediatric IBD phenotypes.
Main Methods:
- Review of recent epidemiological data on pediatric IBD incidence.
- Application and initial assessment of the Paris Classification in pediatric cases.
Main Results:
- Pediatric IBD incidence is increasing in Western and Eastern Europe.
- Paris Classification identifies ileocolonic involvement as characteristic in Crohn's disease (CD).
- Pancolitis is predominant in ulcerative colitis (UC); CD complications and perianal disease rates were similar, though ileal involvement correlated with stricter disease.
Conclusions:
- Nationwide registries are vital for accurate pediatric IBD epidemiological data.
- The Paris Classification is a valuable tool for determining pediatric IBD phenotypes and guiding clinical practice.
Abstract:
New epidemiological data suggest that the incidence of inflammatory bowel disease (IBD) is increasing. As a result the burden of disease accounts for more strains to the health care system. The clinical variability queries whether disease characteristics are related to clinical outcome. Our aim was to delineate the latest results of incidence trends in pediatric IBD and to compare the first experiences with Paris Classification. Incidence of pediatric IBD has been increasing in Western Europe and in Eastern Europe. To better characterize IBD, Paris Classification was introduced and validated recently. Ileocolonic involvement is the most characteristic disease location in Crohn's disease (CD) based on applying Paris Classification. The rate of perianal disease and complicated behaviour in CD was similar. It is of interest that CD patients with colonic involvement were less likely to have stricturing disease compared with patients with ileal involvement. In addition, pancolitis dominated in ulcerative colitis (UC). However, most countries lack prospective, nationwide epidemiological studies to estimate incidence trends. This review emphasizes the importance of nationwide registries that enroll all pediatric IBD cases serving reliable data for "everyday practice." These first reports have shown that Paris Classification is a useful tool to determine the pediatric IBD phenotype.
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