Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Human Genetics01:28

Human Genetics

2.0K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
2.0K
Cancer Prevention02:59

Cancer Prevention

6.5K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
6.5K
Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

1.3K
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
1.3K
Gene-Environment Interactions01:20

Gene-Environment Interactions

1.4K
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
1.4K
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

1.5K
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
1.5K
Pharmacogenetics and Pharmacogenomics: Overview01:29

Pharmacogenetics and Pharmacogenomics: Overview

253
Pharmacogenetics and pharmacogenomics examine how genetic factors influence an individual's response to drugs. While pharmacogenetics focuses on the impact of specific genetic variants on drug effects, pharmacogenomics takes a broader approach, studying how genetic variation across populations contributes to differences in drug responses. These fields aim to explain why individuals may experience varying levels of efficacy or adverse reactions to the same medication.Variability in drug...
253

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Opportunistic Screening of High-Risk Breast Cancer Variants in Hospital Biobank Setting.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology·2026
Same author

High-Resolution Genotyping of Formalin-Fixed Tissue Accurately Estimates Polygenic Risk Scores in Human Diseases.

Laboratory investigation; a journal of technical methods and pathology·2024
Same author

Author Correction: The power of genetic diversity in genome-wide association studies of lipids.

Nature·2023
Same author

Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population.

Nature·2023
Same author

FinnGen provides genetic insights from a well-phenotyped isolated population.

Nature·2023
Same author

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.

Genome biology·2022

Related Experiment Video

Updated: Apr 30, 2026

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
06:07

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System

Published on: October 22, 2020

6.7K

Genetics and smoking.

Anu Loukola, Jenni Hällfors, Tellervo Korhonen

    Current Addiction Reports
    |April 30, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Genetic studies reveal nicotinic receptor genes significantly influence smoking behavior. Despite modest explained variance, research highlights chromosome 15q25 and potential links between nicotine dependence, schizophrenia, and gene-environment interactions.

    Keywords:
    AddictionGenesGenome-wide associationNicotineNicotine metabolismNicotinic receptorsTobacco

    More Related Videos

    Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
    09:50

    Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke

    Published on: February 12, 2015

    11.3K
    Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
    10:47

    Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface

    Published on: February 21, 2011

    33.9K

    Related Experiment Videos

    Last Updated: Apr 30, 2026

    Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
    06:07

    Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System

    Published on: October 22, 2020

    6.7K
    Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
    09:50

    Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke

    Published on: February 12, 2015

    11.3K
    Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
    10:47

    Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface

    Published on: February 21, 2011

    33.9K

    Area of Science:

    • Genetics
    • Epidemiology
    • Pharmacology

    Background:

    • Smoking is a leading preventable cause of death globally, linked to cardiovascular disease and cancers.
    • Nicotine intake, its effects, and metabolism involve complex biological pathways, some not fully understood.
    • Genetic factors play a role in smoking behavior, but the explained phenotypic variance is currently modest.

    Purpose of the Study:

    • To review recent advancements in the genetics and genetic epidemiology of smoking behavior.
    • To focus on the genetic contribution of the nicotinic receptor gene cluster at chromosome 15q25.
    • To explore novel pathways in nicotine dependence and schizophrenia, and gene-environment interactions in smoking.

    Main Methods:

    • Genome-wide association study (GWAS) meta-analyses.
    • Review of genetic studies on smoking behavior and nicotine metabolism.
    • Examination of genetic epidemiology and gene-environment interactions.

    Main Results:

    • Genome-wide association studies consistently identify variations in nicotinic receptor subunit genes as major contributors to smoking traits.
    • Other genes, including those for nicotine-metabolizing enzymes, are implicated.
    • The proportion of phenotypic variance explained by identified genetic variants remains modest.

    Conclusions:

    • Nicotinic receptor genes, particularly those on chromosome 15q25, are strongly associated with smoking behavior.
    • Emerging evidence suggests shared pathophysiology between nicotine dependence and schizophrenia.
    • Gene-environment interactions are crucial in understanding the complex etiology of smoking behavior.