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Updated: Apr 30, 2026
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Staphylococcus aureus infections in children in an Iranian referral pediatric hospital
Insights
This study found a high prevalence of Methicillin-Resistant Staphylococcus aureus (MRSA) infections in pediatric patients in Iran. Both hospital-associated and community-associated MRSA were frequently identified, highlighting the need for optimized antimicrobial strategies.
Area of Science:
- Pediatric Infectious Diseases
- Clinical Microbiology
- Epidemiology
Background:
- Staphylococcus aureus causes diverse infections, including skin, soft tissue, respiratory, and bloodstream infections.
- Understanding the underlying conditions of patients with S. aureus infections is crucial for effective management.
- This study focuses on pediatric patients in an Iranian referral hospital.
Purpose of the Study:
- To evaluate the underlying conditions of pediatric patients diagnosed with Staphylococcus aureus infections.
- To determine the prevalence and characteristics of S. aureus infections in a specific Iranian pediatric hospital setting.
Main Methods:
- Retrospective analysis of medical records for patients diagnosed with S. aureus infections.
- Data collected included demographics, admission reasons, culture sites, hospital stay duration, and methicillin susceptibility.
- Study period: November 2011 to March 2013.
Main Results:
- Jaundice, abscess, and cellulitis were the most frequent diagnoses.
- Wound infections were the most common infection site (35%), followed by blood (20%) and skin/soft tissue (19%).
- A high proportion of Methicillin-Resistant Staphylococcus aureus (MRSA) infections (79%) was observed, with significant rates in both Hospital-Associated (HA-MRSA) and Community-Associated (CA-MRSA) cases.
Conclusions:
- High frequency of MRSA identified in both HA-MRSA and CA-MRSA isolates.
- Findings underscore the need for strategic optimization of antimicrobial use.
- Further research into effective treatment and prevention strategies for MRSA in pediatric populations is warranted.
Introduction:
Staphylococcus aureus is associated with various infections ranging from skin and soft tissues such as surgical site infections and abscesses to lower respiratory tracts and bloodstream. The aim of this study was to evaluate underlying condition of patients with S. aureus infections in an Iranian referral pediatric Hospital.
Material And Methods:
Information was extracted retrospectively from the medical records of patients who were diagnosed with S. aureus infections. Data obtained about the study subjects included basic demographics, reason for admission, culture site, length of hospital stay, and methicillin susceptibility.
Results:
The underlyning condition of of patients with S. aureus infection during November 2011 and March 2013 were included in the study. The most frequent diagnosis in patients with S. aureus infection was jaundice (12%), abscess (10%), cellulitis (10%), wound infection (8%), septic arthritis (7%) and sezeire (5%). Wound was the most common infection sites among all subjects 34/98 (35%) following by blood (20/98, 20%) as well as skin and soft tissue (19/98, 19%). The proportion of MRSA infections among all S. aureus isolates was 79% (77/98) during the study period. In addition, 58/74 (78%) met the definition of Hospital-Associated Methicillin-Resistant S. aureus (HA-MRSA) infections and the rest; 20/24 patients (83%), were classified as Community-Associated Methicillin-Resistant S. aureus (CA- MRSA).
Conclusion:
In our study, the high frequency of MRSA was found not only in HA S. aureus but also in CA S. aureus isolates; therefore, the strategic goals to optimize antimicrobial use including
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