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Antibiotics in South Indian coastal sea and farmed prawns (Penaeus monodon)
Venkatesh Palaniyappan1, Arun Kumar Nagalingam, Hari Prasad Ranganathan
1a Department of Pharmaceutical Analysis , Sir C R Reddy college of Pharmaceutical Sciences , Eluru , Andhra Pradesh , India.
Abstract:
Sulphonamides and chloramphenicol antibiotics were analysed by using liquid chromatography-tandem mass spectrometry (LC-MS/MS) in sea and farmed prawn (Penaeus monodon) samples obtained from the coastal region of southern India during 2011-2012. Average recoveries were 77-99% and precision was between 1% and 8%. The results revealed that in sea prawn samples neither of the two antibiotics was detected, but in farmed samples from coastal Andhra Pradesh some sulphonamides were detected in a concentration range greater than the maximum residual limit as set by Council Directive 2377/90 EC.
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