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Updated: Apr 30, 2026

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Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis
Published on: March 3, 2023
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Microwave liver ablation and dark urine
F Ausania1, R Carracedo Iglesias, M Casal Rivas
1Hospital Xeral, Vigo, Spain.
Summary
Microwave-assisted liver resection can cause intraoperative hemoglobinuria. This report details the first case of acute hemolysis, a serious complication, following this surgical technique.
Area of Science:
- Hepatobiliary Surgery
- Minimally Invasive Techniques
- Surgical Complications
Background:
- Microwave-assisted liver resection offers advantages for hemostasis, particularly in challenging cases.
- Conventional methods may not always achieve optimal hemostasis during liver resection.
- The use of microwave energy in surgery is an evolving area.
Observation:
- Intraoperative hemoglobinuria has been noted as a potential adverse effect of prolonged microwave administration.
- This specific case involved a patient undergoing microwave-assisted liver resection.
- The patient presented with signs and symptoms indicative of hemolysis.
Findings:
- The study describes the first documented instance of acute hemolysis directly linked to microwave-assisted liver resection.
- Hemolysis occurred as a secondary complication following the procedure.
- This highlights a previously unrecognized risk associated with the technique.
Implications:
- Clinicians should be aware of the potential for acute hemolysis following microwave-assisted liver resection.
- Further research is needed to understand the mechanisms and incidence of this complication.
- Strategies to mitigate or monitor for hemolysis during and after this procedure may be required.

