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Related Experiment Videos

Surgery for recurrent colorectal carcinoma--is it worthwhile?

S G Pollard1, R Macfarlane, W G Everett

  • 1Department of Surgery, Addenbrooke's Hospital, Cambridge.

Annals of the Royal College of Surgeons of England
|September 1, 1989
PubMed
Summary

Second surgeries for recurrent colorectal cancer offer curative potential for nearly half of patients. Palliative procedures can also provide significant symptom relief and improve survival outcomes.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Gastroenterology

Background:

  • Colorectal cancer recurrence presents significant challenges for patient management.
  • Early detection of recurrent colorectal cancer is crucial for treatment efficacy.

Purpose of the Study:

  • To evaluate the outcomes of a second operation for recurrent colorectal cancer.
  • To assess the efficacy of potentially curative versus palliative surgical interventions.

Main Methods:

  • Retrospective analysis of 45 patients undergoing reoperation for recurrent colorectal cancer.
  • Evaluation of survival rates, palliation success, and operative mortality.

Main Results:

  • Recurrence typically developed within 2 years of initial surgery.

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  • Potentially curative reoperation achieved 71% 2-year survival and 29% 5-year survival.
  • Palliative surgery was beneficial in 64% of cases, with a mean survival of 10 months.
  • Tumor bulk removal improved palliation and lowered mortality; resection superior to bypass in obstruction.

    • Conclusions:

    • Second-line surgery for recurrent colorectal cancer can offer meaningful survival benefits and palliation.
    • Predicting long-term survival after metastasis resection remains challenging.
    • Routine follow-up has limited success in detecting asymptomatic recurrence.