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Related Concept Videos

Factors Influencing Drug Absorption: Disease States and Pharmacology01:25

Factors Influencing Drug Absorption: Disease States and Pharmacology

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Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
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Effect of Hepatic Disease on Pharmacokinetics: Active Drug, Metabolite and Fraction of Metabolized Drug01:14

Effect of Hepatic Disease on Pharmacokinetics: Active Drug, Metabolite and Fraction of Metabolized Drug

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In pharmacotherapy, monitoring drug concentrations is paramount, especially for drugs whose therapeutic effects hinge on both the active compound and its metabolite. Hepatic impairment profoundly influences drug potency by altering liver function. If the drug is more potent than its metabolite, impaired liver function amplifies drug activity due to elevated drug concentration levels. Conversely, if the metabolite holds greater potency, diminished liver function diminishes drug activity by...
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Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

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In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
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Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment01:08

Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

379
Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...
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Drug Administration and Therapy Phases: Overview01:26

Drug Administration and Therapy Phases: Overview

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Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
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Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

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Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
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Related Experiment Video

Updated: Apr 30, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

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[Clinical pharmacy and surgery: Review].

A Jarfaut1, Y Nivoix1, D Vigouroux2

  • 1Service de pharmacie, hôpitaux universitaires de Strasbourg, 1, avenue Molière, 67098 Strasbourg, France.

Annales Pharmaceutiques Francaises
|May 1, 2014
PubMed
Summary
This summary is machine-generated.

Clinical pharmacy services in surgical settings optimize patient drug management and reduce adverse events. This review highlights key activities and indicators, confirming clinical and economic value.

Keywords:
ActivitiesActivitésChirurgieClinicCliniqueImpactIndicateursIndicatorsPharmaciePharmacySurgery

Related Experiment Videos

Last Updated: Apr 30, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

33.9K

Area of Science:

  • Clinical Pharmacy
  • Surgical Services
  • Drug Management

Context:

  • Clinical pharmacy is integral to hospital activities, with reviews showing significant value.
  • Surgical services face risks of adverse drug events, necessitating optimized pharmaceutical care.
  • Previous research focused on medical patients, leaving surgical patient care less explored.

Purpose:

  • To profile clinical pharmacy activities in surgical services.
  • To identify key performance indicators for clinical pharmacy in surgery.
  • To evaluate the impact of clinical pharmacy on surgical patient outcomes.

Summary:

  • A literature review of 21 English or French papers (2000-2013) from PubMed focused on clinical pharmacy in surgery.
  • Predominant activities included medication history and therapeutic drug monitoring (antibiotics, anticoagulants).
  • Identified indicators comprised activity metrics (interventions, acceptance rates, workload) and impact metrics (clinical, economic).

Impact:

  • Clinical pharmacy development in surgical patient care is documented.
  • Evidence suggests clinical pharmacy provides significant clinical and economic value, similar to medical patient care.
  • Optimized drug management in surgery can lead to improved patient safety and healthcare economics.