Related Experiment Video
Updated: Apr 30, 2026
Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma
Published on: January 22, 2022
Evaluation of SprayShield™ Adhesion Barrier in a single center: randomized controlled study in 15 women undergoing
Garri Tchartchian1, Andreas Hackethal, Anja Herrmann
1Klinik für Minimal Invasive Chirurgie, 14129, Berlin-Zehlendorf, Germany.
Objective:
The objective of this study was to evaluate the safety and efficacy of SprayShield™ Adhesion Barrier in preventing and/or reducing postoperative adhesion during gynecological surgery.
Design:
This was a prospective, controlled, blinded, and randomized study. Patient blinding was performed intraoperatively. Subjects were randomly assigned to the SprayShield™ or the control group in a 2:1 ratio.
Setting:
The study was conducted at the Clinic of Gynaecology and Obstetrics, at the University Hospital for Gynecology in Germany.
Patients:
Fifteen patients participated in this study; nine patients were assigned to the SprayShield™ and six patients to the control group.
Interventions:
During first operation (FLL) in the SprayShield™ group, the agent was applied to all myomectomy suture lines. Patients in the control group did not receive any anti-adhesion treatment, only good surgical practice. A second-look laparoscopy (SLL) was performed 8-12 weeks after myomectomy to evaluate adhesion formation.
Main Outcome Measures:
Main outcome measures were incidence, severity, and extent of uterine adhesions.
Results:
No significant differences were found between the two study groups.
Conclusions:
SprayShield™ is easy to use. No serious adverse event related to SprayShield™ was observed. Efficacy data are inconclusive regarding the performance of SprayShield™. Further studies are needed to better understand this performance.
More Related Videos
03:07Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
Published on: August 19, 2025
03:57Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
Published on: April 28, 2026