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In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Value of dual-source computed tomography in evaluating left ventricular function in patients with coronary heart
1Department of Radiology, Affiliated Nanshan Hospital of Guangdong Medical College, Shenzhen, Guangdong, China bixianshen123@163.com.
Insights
Dual-source computed tomography (DSCT) accurately assesses left ventricular function in coronary heart disease (CHD) patients. DSCT shows comparable results to echocardiography (ECG), especially in diabetic CHD patients.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Left ventricular function is crucial for cardiovascular health.
- Assessing left ventricular function aids in managing coronary heart disease (CHD).
- Diabetes mellitus is a significant comorbidity in CHD patients, potentially affecting cardiac function.
Purpose of the Study:
- To evaluate the accuracy of dual-source computed tomography (DSCT) in assessing left ventricular function.
- To compare DSCT measurements with echocardiography (ECG) in patients with CHD.
- To investigate the impact of type II diabetes on left ventricular function parameters in CHD patients.
Main Methods:
- Cardiac DSCT and ECG examinations were performed on 58 CHD patients.
- Ejection fraction (EF), end-systolic volume (ESV), stroke volume (SV), and end-diastolic volume (EDV) were measured.
- Statistical correlation analysis was used to compare DSCT and ECG results.
Main Results:
- DSCT showed strong correlations with ECG for EF (r=0.70), ESV (r=0.87), SV (r=0.83), and EDV (r=0.90).
- CHD patients with type II diabetes exhibited higher mean ESV and EDV compared to non-diabetic patients.
- Mean EF was lower in CHD patients with type II diabetes.
Conclusions:
- DSCT is a reliable and practical tool for evaluating left ventricular function in CHD patients.
- DSCT provides accurate measurements comparable to ECG for key functional parameters.
- Type II diabetes is associated with altered left ventricular volumes and reduced ejection fraction in CHD patients.
Abstract:
We aimed to assess parameters reflecting left ventricular function by dual-source computed tomography (DSCT) with echocardiography (ECG) as control. Fifty-eight patients with coronary heart disease (CHD) were recruited from January to June 2011; 29 CHD patients had type II diabetes. All patients were assessed by cardiac DSCT and ECG examination. DSCT and ECG correlated well for ejection fraction (EF) (r = 0.70), end-systolic volume (ESV) (r = 0.87), stroke volume (SV) (r = 0.83), and end-diastolic volume (EDV) (r = 0.90). The mean ESV and EDV values measured by the two methods in CHD patients with type II diabetes were higher than those in non-diabetic patients, whereas the mean EF was lower. DSCT is an accurate and practical method for assessing left ventricular function.
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