Related Experiment Video
Updated: Apr 30, 2026

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
Published on: April 4, 2012
Development of automatic visceral fat volume calculation software for CT volume data
Mitsutaka Nemoto1, Tusufuhan Yeernuer2, Yoshitaka Masutani1
1Department of Radiology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Objective:
To develop automatic visceral fat volume calculation software for computed tomography (CT) volume data and to evaluate its feasibility.
Methods:
A total of 24 sets of whole-body CT volume data and anthropometric measurements were obtained, with three sets for each of four BMI categories (under 20, 20 to 25, 25 to 30, and over 30) in both sexes. True visceral fat volumes were defined on the basis of manual segmentation of the whole-body CT volume data by an experienced radiologist. Software to automatically calculate visceral fat volumes was developed using a region segmentation technique based on morphological analysis with CT value threshold. Automatically calculated visceral fat volumes were evaluated in terms of the correlation coefficient with the true volumes and the error relative to the true volume.
Results:
Automatic visceral fat volume calculation results of all 24 data sets were obtained successfully and the average calculation time was 252.7 seconds/case. The correlation coefficients between the true visceral fat volume and the automatically calculated visceral fat volume were over 0.999.
Conclusions:
The newly developed software is feasible for calculating visceral fat volumes in a reasonable time and was proved to have high accuracy.
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

