Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epilepsy ll: Types01:22

Epilepsy ll: Types

47
Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
47
Seizures: Classification01:13

Seizures: Classification

2.5K
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
2.5K
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

1.7K
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.7K
Seizures l: Introduction01:20

Seizures l: Introduction

42
Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
42
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

15
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
15
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

1.1K
Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Regional DTI Metrics as Predictor of Early Developmental Outcome in Term Neonates with HIE.

Indian journal of pediatrics·2026
Same author

Current practice patterns among Indian neurologists in the Evaluation and management of Normal Pressure Hydrocephalus: A nationwide cross-sectional survey.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Cerebral venous thrombosis-related stroke in India: Clinical patterns, risk factors, and outcomes from the hospital-based stroke registry programme.

The Indian journal of medical research·2026
Same author

American Heart Association/American Stroke Association 2026 Guideline for the Early Management of Patients with Acute Ischemic Stroke: Pediatric Perspective.

Indian pediatrics·2026
Same author

Images in Neurology: Cortical Encephalitis in CNS Tuberculosis.

The Neurohospitalist·2026
Same author

Over 600 million people aged 18-65 will have headache tomorrow: global 1-day prevalence and recall bias from a meta-analysis of individual participant data (N = 38,512) from the general populations of 15 countries.

The journal of headache and pain·2026

Related Experiment Video

Updated: Apr 30, 2026

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

3.5K

Cryptogenic gelastic epilepsy: a pediatric case vignette.

Devendra Mishra1, Monica Juneja2, Taruna Chutani3

  • 1Associate Professor, Department of Paediatrics, Lok Nayak Hospital, Maulana Azad Medical College , Delhi, India .

Journal of Clinical and Diagnostic Research : JCDR
|May 1, 2014
PubMed
Summary

Gelastic seizures, a rare epilepsy type causing epileptic laughter, are often linked to hypothalamic hamartomas. This case highlights a rare instance of cryptogenic gelastic seizures without a hypothalamic hamartoma, suggesting a focal origin despite normal MRI.

Keywords:
ChildHypothalamic hamartomaLaughing episodes

More Related Videos

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

22.8K
Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy
09:29

Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy

Published on: August 17, 2021

2.5K

Related Experiment Videos

Last Updated: Apr 30, 2026

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

3.5K
Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

22.8K
Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy
09:29

Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy

Published on: August 17, 2021

2.5K

Area of Science:

  • Neurology
  • Epileptology
  • Pediatric Neurology

Background:

  • Gelastic seizures are typically associated with hypothalamic hamartomas.
  • These seizures manifest as episodes of unprovoked, often inappropriate, laughter.
  • The rarity of gelastic seizures necessitates detailed case reporting for better understanding.

Observation:

  • A case of gelastic seizures was observed without evidence of a hypothalamic hamartoma.
  • Magnetic Resonance Imaging (MRI) of the brain revealed no structural abnormalities.
  • Electroencephalogram (EEG) and clinical presentation suggested a focal origin for the seizures.

Findings:

  • This case represents a rare instance of cryptogenic gelastic seizures.
  • The absence of a hypothalamic hamartoma challenges typical etiologies.
  • Focal epilepsy was indicated by EEG and clinical seizure characteristics.

Implications:

  • This case expands the differential diagnosis for gelastic seizures.
  • It underscores the importance of considering focal epilepsy in cryptogenic cases.
  • Further research into non-hamartoma-related gelastic seizures is warranted.