Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

54
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
54
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

44
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
44
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

20
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
20
Atherosclerosis IV: Nursing Management01:23

Atherosclerosis IV: Nursing Management

611
Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...
611
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

30
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
30
Stroke: Introduction and Types01:29

Stroke: Introduction and Types

55
A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
55

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the Impact of Platelet-Derived Growth Factor D in Pulmonary Hypertension Development.

Pulmonary circulation·2025
Same author

The use of Tranexamic Acid in Case of Patient with Intracerebral Hemorrhage After a Coronary Procedure-Case Report.

Medical archives (Sarajevo, Bosnia and Herzegovina)·2025
Same author

The Role of Modifying Risk Factors as Well as Body Mass Index, Waist Circumference and Hip to Waist Ratio as Anthropometric Indicators and Parameters of Obesity in the Occurence of Stroke.

Materia socio-medica·2024
Same author

Correlation Between Carotid Stenosis and Pulsatile Index Measured by Transcranial Doppler.

Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH·2024
Same author

Favorite colors of patients with drug-resistant epilepsy: pilot study.

Acta neurologica Belgica·2024
Same author

Transcription factor GATA6 promotes migration of human coronary artery smooth muscle cells <i>in vitro</i>.

Frontiers in physiology·2022

Related Experiment Video

Updated: Apr 30, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

9.4K

Post stroke depression.

Azra Alajbegovic, Jasminka Djelilovic-Vranic, Amina Nakicevic

    Medical Archives (Sarajevo, Bosnia and Herzegovina)
    |May 3, 2014
    PubMed
    Summary

    Depression after stroke is more common in younger women and those with left-hemisphere strokes and higher disability. This impacts post-stroke quality of life.

    Area of Science:

    • Neurology
    • Psychiatry
    • Public Health

    Background:

    • Comorbidity of depression and stroke significantly reduces post-stroke quality of life.
    • Stroke sequelae influence quality of life and the occurrence of post-stroke depression.
    • Investigated depression occurrence in stroke patients using the Hamilton scale and disability using the NIHSS scale.

    Purpose of the Study:

    • Comparative analysis of depression after stroke based on gender, age, lesion side, and neurological deficit severity.
    • To understand the relationship between stroke characteristics and depression.
    • To identify risk factors for post-stroke depression.

    Main Methods:

    • Study included 210 stroke patients (105 male, 105 female) treated at the Neurology Clinic, Clinical Center of Sarajevo University.

    More Related Videos

    Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint
    06:15

    Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint

    Published on: January 9, 2026

    187
    Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits
    05:08

    Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits

    Published on: March 15, 2024

    2.1K

    Related Experiment Videos

    Last Updated: Apr 30, 2026

    A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
    04:38

    A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

    Published on: May 22, 2019

    9.4K
    Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint
    06:15

    Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint

    Published on: January 9, 2026

    187
    Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits
    05:08

    Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits

    Published on: March 15, 2024

    2.1K
  • Mean patient age was 67.12 ± 9.5 years; 65% had ischemic stroke.
  • Depression assessed by Hamilton scale; disability by NIHSS scale.

    • Main Results:

    • Depression was more prevalent in younger patients (52-60 years) (39.2%) compared to older patients (61-70 years) (32%).
    • Significantly more women (63.8%) experienced depression compared to men (27.2%) (p=0.00019).
    • Depression was more frequent in patients with stroke in the left hemisphere medial localization (63%) and higher NIHSS scores (average 16.07).

    Conclusions:

    • Post-stroke depression is more frequent in younger patients.
    • Female patients exhibit higher rates of depression post-stroke.
    • Higher disability scores and left medial hemisphere strokes are associated with increased depression prevalence.