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The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups
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Opening the door to innovation.

Janine Schuurman1, Yvo F Graus1, Aran F Labrijn1

  • 1Genmab; Utrecht, The Netherlands.

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This study details a successful open innovation initiative in drug development, highlighting an academia-industry alliance that created novel therapeutic antibody technology platforms.

Keywords:
Duobody technologyFab-arm exchangeOpen innovationTechnology platformbispecific antibodiesdrug developmentimmunotherapy

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Area of Science:

  • Biotechnology
  • Pharmaceutical Sciences
  • Drug Discovery

Background:

  • Open innovation is increasingly adopted in the pharmaceutical industry.
  • Academia-industry collaborations are crucial for driving innovation.
  • Traditional drug development models are evolving.

Purpose of the Study:

  • To provide a personal perspective on a successful knowledge-driven open innovation project.
  • To illustrate the formation and impact of an academia-industry alliance.
  • To describe the development of technology platforms for novel therapeutic antibodies.

Main Methods:

  • Review of a specific academia-industry alliance case study.
  • Analysis of knowledge transfer and platform development.
  • Focus on the generation of therapeutic antibodies with unique characteristics.

Main Results:

  • Successful establishment of technology platforms through open innovation.
  • Generation of therapeutic antibodies with novel and enhanced properties.
  • Demonstration of a viable model for collaborative drug development.

Conclusions:

  • Open innovation, particularly through academia-industry partnerships, can accelerate the development of advanced therapeutics.
  • Knowledge-driven approaches are key to creating impactful technology platforms.
  • This model facilitates the creation of therapeutic antibodies with improved functionalities.