Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation

1.1K
Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
There are three main types of inductively coupled plasma atomic emission spectroscopy  (ICP-AES) instruments: sequential, simultaneous multichannel, and Fourier transform instruments, with the latter being less commonly used....
1.1K
Controlled-Current Coulometry: Overview01:27

Controlled-Current Coulometry: Overview

900
Controlled current coulometry, also known as amperostatic coulometry, is a technique used in electrochemical analysis to measure the quantity of a substance through the controlled passage of current. It involves the application of a constant current to an electrochemical cell containing the analyte of interest. As the current flows through the cell, the analyte undergoes a redox reaction at the electrode surface, resulting in a charge transfer. By monitoring the time required for a certain...
900
Controlled-Potential Coulometry: Electrolytic Methods01:17

Controlled-Potential Coulometry: Electrolytic Methods

916
Controlled-potential coulometry, also known as potentiostatic coulometry, employs a three-electrode system in which the working electrode's potential is precisely regulated using a potentiostat. Platinum working electrodes are utilized for positive potentials, while mercury pool electrodes are favored for extremely negative potentials. The platinum counter electrode is separated from the analyte using a membrane or salt bridge to avoid interference in the analysis.
The chosen potential...
916
Bioreactor Controls-I01:28

Bioreactor Controls-I

94
Maintaining optimal conditions within fermenters is essential for maximizing microbial productivity and ensuring process efficiency. This lesson focuses on key parameters—temperature, foam, pH, carbon dioxide, oxygen, and pressure—and their precise measurement and control strategies in fermentation systems.Temperature ControlTemperature regulation is critical due to the exothermic nature of many fermentation processes. In small laboratory fermenters, temperature is commonly...
94
Bioreactor Controls-II01:18

Bioreactor Controls-II

76
In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the...
76
Open and closed-loop control systems01:17

Open and closed-loop control systems

2.0K
Control systems are foundational elements in automation and engineering. They are broadly categorized into open-loop and closed-loop systems. These classifications hinge on the presence or absence of feedback mechanisms, significantly influencing the system's performance, complexity, and application.
An open-loop control system operates without feedback from the output. It consists of two primary elements: the controller and the controlled process. The controller receives an input signal...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complex Deep Neural Networks for Denoising Ultra-Fast Submillimeter T2*-weighted Imaging and Quantitative Susceptibility Mapping.

European journal of radiology artificial intelligence·2026
Same author

A Porcine Model of Intervertebral Disc Injury Recapitulates Human Discogenic Pain Via Notochordal Cell Loss and Pain-Inducing Nucleus Pulposus Cell Emergence.

JOR spine·2026
Same author

Coffee Consumption and Improved Liver Outcomes: Clinical, Imaging, and Proteomic Evidence From the UK Biobank.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2026
Same author

The "Brain's Traffic Map" Reveals Neural Pathways Linked to Coronary Microvascular Dysfunction in Women.

Brain and behavior·2026
Same author

Refined liver MRI-derived cT1 thresholds capturing hepatic fat fraction enhance mortality risk prediction.

JHEP reports : innovation in hepatology·2026
Same author

Hierarchical organ aging signatures from routine abdominal CT add incremental disease risk stratification beyond blood biomarkers.

medRxiv : the preprint server for health sciences·2026

Related Experiment Video

Updated: Apr 30, 2026

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser
09:00

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser

Published on: June 28, 2018

9.3K

LabVIEW-based control software for para-hydrogen induced polarization instrumentation.

Jose Agraz1, Alexander Grunfeld1, Debiao Li1

  • 1Department of Bioengineering, University of California, Los Angeles, California 91791, USA.

The Review of Scientific Instruments
|May 3, 2014
PubMed
Summary

Automating para-hydrogen induced polarization (PHIP) enhances magnetic resonance imaging (MRI) signal acquisition. This precise control enables reproducible hyperpolarization of contrast agents for cell metabolism studies.

More Related Videos

Automation of Mode Locking in a Nonlinear Polarization Rotation Fiber Laser through Output Polarization Measurements
14:18

Automation of Mode Locking in a Nonlinear Polarization Rotation Fiber Laser through Output Polarization Measurements

Published on: February 28, 2016

11.0K
Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer
10:11

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

Published on: April 19, 2021

3.0K

Related Experiment Videos

Last Updated: Apr 30, 2026

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser
09:00

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser

Published on: June 28, 2018

9.3K
Automation of Mode Locking in a Nonlinear Polarization Rotation Fiber Laser through Output Polarization Measurements
14:18

Automation of Mode Locking in a Nonlinear Polarization Rotation Fiber Laser through Output Polarization Measurements

Published on: February 28, 2016

11.0K
Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer
10:11

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

Published on: April 19, 2021

3.0K

Area of Science:

  • Biophysics
  • Medical Imaging
  • Metabolic Engineering

Background:

  • Cellular metabolism is crucial for disease diagnosis and treatment.
  • Para-Hydrogen induced polarization (PHIP) significantly amplifies MRI signals (>10,000 fold).
  • PHIP enables MRI of cellular metabolic processes by hyperpolarizing endogenous contrast agents.

Purpose of the Study:

  • To address the lack of precise control in manual PHIP instrumentation.
  • To develop an automated system for reproducible hyperpolarization.
  • To facilitate rapid prototyping of PHIP instruments for evaluating contrast agents.

Main Methods:

  • Designed and implemented a LabVIEW-based computer program.
  • Automated control of gas delivery, sample manipulation, and environmental parameters (pressure, temperature).
  • Integrated monitoring of static magnetic field (Bo) and radio frequency (RF) irradiation timing.

Main Results:

  • Achieved precise and automated control over the PHIP hyperpolarization process.
  • Successfully demonstrated the hyperpolarization of hydroxyethylpropionate.
  • Validated the system's capability for reproducible results.

Conclusions:

  • Automated control enhances the reproducibility of PHIP.
  • The developed software accelerates the evaluation of (13)C-based contrast agents.
  • This advancement supports molecular imaging and the study of cell metabolism.