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Published on: April 23, 2018
Thymine vanadyl(II) compound as a diabetic drug model: chemical spectroscopic and antimicrobial assessments
Mohamed Y El-Sayed1, Moamen S Refat2
1Department of Chemistry, Faculty of Science, Zagazig University, Egypt; Faculty of Applied Medical Science, Al Jouf University-Al Qurayate, Saudi Arabia.
Abstract:
The aim of this study was to synthesize a novel bifunctionalized thymine vanadyl(II) compound. The solid vanadyl(II) compound has been characterized by elemental analyses (CHN), Raman laser, infrared spectra, molar conductivity, electronic spectra, thermogravimetric analyses (TGA), scanning electron microscopy (SEM) and X-ray powder diffraction (XRD) studies. Electronic and magnetic measurements have confirmed that the speculated geometry of vanadyl(II) compound is square pyramidal geometry. The microbial test was performed for the vanadyl complex against some kinds of bacteria and fungi. The results suggested that [VO(Thy)2] adduct has an anti-diabetic profile.
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