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Related Experiment Video

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Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

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Published on: January 24, 2020

Towards an aging-specific cognitive phenotype: the freedom house study.

Donald R Royall¹, Raymond F Palmer, Laura K Chiodo

¹a Departments of Psychiatry, Medicine, and Family and Community Medicine , The University of Texas Health Science Center , San Antonio , Texas , USA.

Experimental Aging Research

|May 3, 2014

Summary

This study identifies a distinct aging-specific cognitive phenotype (ASCP) characterized by declining visuospatial skills and improving verbal fluency, differentiating true aging from disease effects.

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Area of Science:

Gerontology
Cognitive Neuroscience
Psychometrics

Background:

Previous latent growth curve (LGC) models analyzed cognitive changes in aging volunteers.
Growth mixture modeling (GMM) was employed to identify distinct cognitive trajectories.

Purpose of the Study:

To describe an aging-specific cognitive phenotype (ASCP).
To differentiate cognitive changes due to aging from those caused by disease.

Main Methods:

Longitudinal assessment of 547 noninstitutionalized individuals aged 70+.
Utilized a comprehensive battery of psychometric measures.

Main Results:

Identified distinct trajectory classes, including one representing "Aging Proper".
The ASCP showed declining visuospatial function and improving verbal fluency.
The ASCP was not linked to memory decline.

Conclusions:

Age-related memory decline may stem from comorbid diseases, not aging itself.
The ASCP aligns with "Right Hemisphere" aging models.
Provides insights into mechanisms of true age-related cognitive changes.