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Related Experiment Video

Updated: Apr 30, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Conservative surgery for ipsilateral breast tumor recurrence.

Jose Vila1, Carlos A Garcia-Etienne, Andrea Vavassori

  • 1Division of Breast Surgery, European Institute of Oncology, Milan, Italy.

Journal of Surgical Oncology
|May 3, 2014
PubMed
Summary

Managing ipsilateral breast recurrence after conservative therapy is debated. Selected patients may benefit from repeat lumpectomy and sentinel node biopsy, challenging mastectomy guidelines for breast cancer recurrence.

Keywords:
IBTRbreast cancer recurrencebreast-conserving surgeryipsilateral breast tumor recurrencelocal recurrenceloco-regional recurrencere-irradiationrepeat lumpectomysalvage mastectomy

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiotherapy

Background:

  • Ipsilateral breast recurrence after conservative therapy presents management challenges.
  • Current guidelines often recommend mastectomy for all breast cancer recurrences.
  • Evidence for repeat breast-conserving surgery is emerging.

Purpose of the Study:

  • To review the rationale and evidence for a second conservative approach in managing ipsilateral breast recurrence.
  • To discuss the oncological safety of repeat lumpectomy and sentinel node biopsy.
  • To address the controversy surrounding breast cancer recurrence management.

Main Methods:

  • Literature review of studies on ipsilateral breast recurrence after conservative therapy.
  • Analysis of current guidelines and emerging evidence.
  • Discussion of surgical and radiotherapeutic management options.

Main Results:

  • Mastectomy is the standard guideline for breast cancer recurrence.
  • Selected patients may be candidates for repeat breast-conserving surgery.
  • Repeat lumpectomy and sentinel node biopsy show potential oncological safety.

Conclusions:

  • The management of ipsilateral breast recurrence requires careful patient selection.
  • Repeat conservative surgery may be a viable option for selected patients.
  • Further evidence is needed to refine guidelines for breast cancer recurrence treatment.