Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Immunological Memory01:23

Immunological Memory

12.3K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
12.3K
Inclusive Fitness00:57

Inclusive Fitness

23.6K
Most altruistic behavior—in which one animal helps another at a cost to themselves—occurs between relatives. Scientists think these altruistic behaviors evolved because they increase the inclusive fitness of the animal providing help.
23.6K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

6.9K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
6.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis, Antiprotozoal Activity, and Physicochemical Evaluation of Benzamido-Menadione Derivatives.

International journal of molecular sciences·2025
Same author

Pharmacomodulation of the Redox-Active Lead Plasmodione: Synthesis of Substituted 2-Benzylnaphthoquinone Derivatives, Antiplasmodial Activities, and Physicochemical Properties.

International journal of molecular sciences·2025
Same author

Recycling honey bee drone brood for sustainable beekeeping.

Journal of economic entomology·2025
Same author

Flight performance of pollen starved honey bees and incomplete compensation through ingestion after early life pollen deprivation.

Frontiers in physiology·2022
Same author

NHR-23 and SPE-44 regulate distinct sets of genes during Caenorhabditis elegans spermatogenesis.

G3 (Bethesda, Md.)·2022
Same author

Sublethal pesticide exposure induces larval removal behavior in honeybees through chemical cues.

Ecotoxicology and environmental safety·2021

Related Experiment Video

Updated: Apr 30, 2026

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model
10:58

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model

Published on: August 29, 2013

10.6K

Trans-generational immune priming in honeybees.

Javier Hernández López1, Wolfgang Schuehly, Karl Crailsheim

  • 1Department of Zoology, Karl-Franzens University of Graz, , Universitätsplatz 2, 8010 Graz, Austria.

Proceedings. Biological Sciences
|May 3, 2014
PubMed
Summary

Honeybee queens primed their offspring against American Foulbrood disease. This trans-generational immune priming (TgIP) enhanced offspring resistance to bacterial infection, showing a potential link to immune cell differentiation.

Keywords:
Paenibacillus larvaeartificial rearinghaemocyteshoneybeesimmune priming

More Related Videos

Preparation of Single-cohort Colonies and Hormone Treatment of Worker Honeybees to Analyze Physiology Associated with Role and/or Endocrine System
08:53

Preparation of Single-cohort Colonies and Hormone Treatment of Worker Honeybees to Analyze Physiology Associated with Role and/or Endocrine System

Published on: September 6, 2016

15.1K
RNAi-mediated Double Gene Knockdown and Gustatory Perception Measurement in Honey Bees Apis mellifera
10:57

RNAi-mediated Double Gene Knockdown and Gustatory Perception Measurement in Honey Bees Apis mellifera

Published on: July 25, 2013

14.3K

Related Experiment Videos

Last Updated: Apr 30, 2026

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model
10:58

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model

Published on: August 29, 2013

10.6K
Preparation of Single-cohort Colonies and Hormone Treatment of Worker Honeybees to Analyze Physiology Associated with Role and/or Endocrine System
08:53

Preparation of Single-cohort Colonies and Hormone Treatment of Worker Honeybees to Analyze Physiology Associated with Role and/or Endocrine System

Published on: September 6, 2016

15.1K
RNAi-mediated Double Gene Knockdown and Gustatory Perception Measurement in Honey Bees Apis mellifera
10:57

RNAi-mediated Double Gene Knockdown and Gustatory Perception Measurement in Honey Bees Apis mellifera

Published on: July 25, 2013

14.3K

Area of Science:

  • Immunology
  • Entomology
  • Genetics

Background:

  • Trans-generational immune priming (TgIP) enhances offspring resistance to pathogens through maternal immune experience.
  • TgIP is crucial for health in social insects like honeybees but its mechanisms in these species are not fully understood.
  • American Foulbrood, caused by Paenibacillus larvae (Pl), is a devastating disease for honeybee colonies.

Purpose of the Study:

  • To investigate the existence and effects of trans-generational immune priming (TgIP) in honeybees.
  • To evaluate the impact of maternal immune stimulation on offspring resistance to Paenibacillus larvae.
  • To explore the correlation between TgIP and immune cell differentiation in honeybee larvae.

Main Methods:

  • Honeybee queens were immune-stimulated with Paenibacillus larvae (Pl).
  • Offspring from stimulated queens were experimentally exposed to Pl spores.
  • Offspring mortality rates were measured to assess immune transfer; haemocyte differentiation was analyzed.

Main Results:

  • Maternal immune priming significantly enhanced offspring resistance to Paenibacillus larvae infection.
  • The study provides direct evidence for trans-generational immune priming effects in honeybees.
  • Immune priming was correlated with the differentiation of prohaemocytes into haemocytes in larvae.

Conclusions:

  • Trans-generational immune priming (TgIP) is a viable mechanism for enhancing honeybee colony health against diseases like American Foulbrood.
  • Priming stimulates immune cell differentiation, suggesting a molecular pathway for TgIP.
  • Further research is needed to fully elucidate the molecular mechanisms underlying TgIP in honeybees.