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Updated: Apr 30, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Psoriasis and comorbidities: links and risks
1Division of Dermatology, Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA.
Psoriasis patients have higher rates of serious health conditions like heart disease and diabetes. Early screening and treatment for these comorbidities are crucial for effective psoriasis management.
Area of Science:
- Dermatology
- Internal Medicine
- Epidemiology
Background:
- Psoriasis is a chronic inflammatory skin condition affecting 2% of the global population.
- Comorbidities in psoriasis have gained significant research attention.
- Understanding these links is vital for holistic patient care.
Purpose of the Study:
- To review epidemiological data on psoriasis comorbidities.
- To explore pathophysiological links between psoriasis and other diseases.
- To discuss therapeutic strategies for managing psoriasis comorbidities.
Main Methods:
- Literature review of studies on psoriasis comorbidities.
- Analysis of epidemiological evidence.
- Synthesis of pathophysiological and therapeutic information.
Main Results:
- Psoriasis is associated with increased prevalence of cardiovascular disease, obesity, diabetes, hypertension, dyslipidemia, metabolic syndrome, nonalcoholic fatty liver disease, cancer, anxiety, depression, and inflammatory bowel disease.
- These conditions occur more frequently in psoriasis patients than in the general population.
- Significant pathophysiological commonalities exist.
Conclusions:
- Comprehensive screening for comorbidities is essential in psoriasis patients.
- Integrated treatment approaches are necessary for optimal management.
- Addressing comorbidities improves overall health outcomes for individuals with psoriasis.
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