Development of an open source software module for enhanced visualization during MR-guided interstitial gynecologic...

Area of Science:

• Biomedical Engineering
• Medical Imaging
• Oncology

Background:

• Gynecologic malignancies are a significant cause of death in women.
• Interstitial brachytherapy is a treatment option for extensive or recurrent disease.
• Precise catheter insertion is critical for effective brachytherapy.

Purpose of the Study:

• To investigate and develop a software solution to assist in interstitial gynecologic brachytherapy.
• To enhance the precision and safety of brachytherapy procedures.
• To integrate intra-operative imaging and virtual planning into the treatment workflow.

Main Methods:

• Developed a software module integrated into the (3D) Slicer platform.
• Enabled real-time processing of intra-operative magnetic resonance imaging (iMRI) data via DICOM.
• Implemented a multi-stage registration of CAD models (template, obturator) to patient MR images.
• Facilitated virtual placement of interstitial needles for pre-procedural planning.

Main Results:

• A functional software module for interstitial gynecologic brachytherapy assistance was realized.
• The module allows for timely processing of iMRI data.
• Virtual placement of brachytherapy devices and needles was enabled, aiding physician planning.

Conclusions:

• The developed software provides a valuable tool for assisting physicians during interstitial gynecologic brachytherapy.
• Integration with iMRI and 3D Slicer enhances pre-operative planning and intra-operative guidance.
• This approach has the potential to improve treatment outcomes for patients with gynecologic malignancies.