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Related Experiment Video

Updated: Apr 30, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
11:17

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

661

Lobectomy vs. segmentectomy for NSCLC (T<2 cm).

Nestor Villamizar1, Scott J Swanson1

  • 1Department of Thoracic Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Annals of Cardiothoracic Surgery
|May 3, 2014
PubMed
Summary
This summary is machine-generated.

For early-stage non-small cell lung cancer (NSCLC) 2 cm or smaller, segmentectomy may offer similar outcomes to lobectomy. This review compares surgical options for peripheral T1N0M0 NSCLC pending further RCT data.

Keywords:
2 cmSegmentectomylobectomylung cancer

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Area of Science:

  • Thoracic Surgery
  • Surgical Oncology
  • Pulmonology

Background:

  • Lobectomy is the established standard for peripheral clinical T1N0M0 non-small cell lung cancer (NSCLC) ≤2 cm.
  • Recent retrospective studies suggest comparable outcomes with segmentectomy for similar tumors.

Purpose of the Study:

  • To comprehensively review and compare lobectomy versus segmentectomy for peripheral clinical T1N0M0 NSCLC ≤2 cm.
  • To provide evidence-based guidance for thoracic surgeons managing these early-stage lung cancers.

Main Methods:

  • Literature review comparing lobectomy and segmentectomy outcomes.
  • Analysis of studies focusing on peripheral clinical T1N0M0 NSCLC ≤2 cm.

Main Results:

  • Numerous publications indicate similar outcomes between segmentectomy and lobectomy for small peripheral NSCLC.
  • The majority of existing comparative data are from retrospective studies.

Conclusions:

  • The optimal surgical approach for peripheral T1N0M0 NSCLC ≤2 cm remains debated.
  • This literature review offers current best evidence pending results from ongoing randomized controlled trials (RCTs).