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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Cancer Therapies02:49

Cancer Therapies

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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

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Related Experiment Video

Updated: Apr 30, 2026

Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice
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Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice

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[New anticancer drugs: much ado about nothing?].

S Zimmermann, D Betticher

    Revue Medicale Suisse
    |May 6, 2014
    PubMed
    Summary

    New cancer drugs, particularly molecularly targeted agents, have improved patient outcomes. Epidemiologic and clinical data show better cure rates and survival times for advanced diseases compared to previous decades.

    Area of Science:

    • Oncology
    • Pharmacology
    • Epidemiology

    Context:

    • The last decade has seen the marketing of numerous novel cancer therapeutics, including many molecularly targeted agents.
    • Assessing the population-wide impact of these new cancer drugs on clinical outcomes presents a significant challenge.
    • Questions arise regarding the true benefit of these often expensive and toxic agents versus their impact on a minority of patients.

    Purpose:

    • To evaluate the overall impact of new cancer drugs, especially molecularly targeted therapies, on patient outcomes.
    • To determine if recent advancements in cancer treatment have led to measurable improvements in cure rates and survival.

    Summary:

    • Analysis of epidemiologic trends and clinical trial data indicates a substantial improvement in patient outcomes over the past 10-20 years.

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  • These improvements are evident in increased cure rates and prolonged survival times for patients with advanced-stage cancer.
  • The data suggests that recent therapeutic developments have contributed positively to the fight against cancer.

    • Impact:

    • Patient outcomes in cancer treatment have significantly improved compared to previous decades.
    • Enhanced cure rates and extended survival times for advanced disease demonstrate progress in oncology.
    • The development and application of new cancer drugs appear to be contributing to a "war on cancer" victory.