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Updated: Apr 30, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Cognitive abilities in preterm and term-born adolescents
Luke A Schneider1, Nicholas R Burns2, Lynne C Giles3
1Research Center for Early Origins of Health and Disease, Robinson Institute, School of Pediatrics and Reproductive Health, University of Adelaide, Adelaide, Australia.
Gestational age (GA) has minimal impact on adolescent cognitive abilities. Prenatal and postnatal environmental factors, like social disadvantage and birth weight, are stronger predictors of cognitive development in adolescents.
Area of Science:
- Developmental neuroscience
- Adolescent psychology
- Cognitive development
Background:
- Cognitive development in adolescents is influenced by various factors.
- Understanding these influences is crucial for early intervention and support.
Purpose of the Study:
- To investigate the impact of prenatal and postnatal factors on cognitive development in adolescents.
- To explore the relationship between neurophysiological measures and cognitive outcomes.
Main Methods:
- Assessed cognitive abilities using Woodcock-Johnson III Tests of Cognitive Abilities.
- Measured corticomotor excitability via transcranial magnetic stimulation and electromyography.
- Employed relative importance regression modeling to analyze factor influences.
Main Results:
- Higher gestational age (GA) correlated with better cognitive abilities and corticomotor excitability.
- Corticomotor excitability was a stronger predictor of cognitive outcome than GA.
- Social disadvantage, birthweight percentile, and height were the strongest predictors of cognitive outcome.
Conclusions:
- Gestational age explains limited interindividual variability in cognitive abilities among neurologically healthy adolescents.
- Reduced brain connectivity may underlie cognitive deficits in preterm children.
- The relative importance of heritability versus the postnatal environment on cognitive development requires further investigation.
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