PTGER4 modulating variants in Crohn's disease.

Matthias Prager1, Janine Büttner, Carsten Büning

  • 1Department of Hepatology and Gastroenterology, Universitätsmedizin Berlin, Charité Campus Mitte, Charitéplatz 1, 10117, Berlin, Germany.

Summary

A specific PTGER4 gene variant, rs7720838, is linked to increased Crohn's disease susceptibility. This variant may also indicate a higher risk for developing stricturing disease behavior in Crohn's disease patients.

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