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Updated: Apr 30, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
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Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

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Precision medicine in oncology standard of care

Lynn Adams

    Seminars in Oncology Nursing
    |May 6, 2014
    PubMed
    Abstract

    Insights

    Advances in understanding tumor genetics and molecular markers have improved treatment options for non-small cell lung cancer and melanoma, offering better outcomes and quality of life.

    Area of Science:

    • Oncology
    • Molecular Biology
    • Genetics

    Background:

    • Metastatic non-small cell lung cancer (NSCLC) and melanoma historically had limited, toxic treatment options.
    • Tumor genetics and molecular markers were not widely utilized in directing standard therapy.

    Purpose of the Study:

    • To review histologic subtypes and staging of NSCLC and melanoma.
    • To examine molecular markers guiding current therapies for these cancers.
    • To inform healthcare professionals about advancements in cancer treatment.

    Main Methods:

    • Literature review of book chapters and journal articles.
    • Inclusion of published clinical guidelines.
    • Synthesis of information on cancer subtypes, staging, and molecular markers.

    Main Results:

    • Understanding tumor genetics has significantly expanded therapeutic strategies.
    • Targeted therapies based on molecular markers offer durable responses.
    • Improved quality of life for patients with advanced NSCLC and melanoma.

    Conclusions:

    • Molecular markers are crucial for directing effective cancer therapies.
    • Nurses require knowledge of genetics and molecular markers to support patients.
    • Personalized medicine approaches are transforming outcomes in metastatic cancers.
    Keywords:
    Precision medicinemolecular targetsoncology standard of care

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