Synthesis and SAR of substituted pyrazolo[1,5-a]quinazolines as dual mGlu(2)/mGlu(3) NAMs

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Facile Preparation of 4-Substituted Quinazoline Derivatives
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Cody J Wenthur1, Ryan D Morrison1, J Scott Daniels1

  • 1Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

Bioorganic & Medicinal Chemistry Letters
|May 6, 2014
PubMed

Keywords:
Metabotropic glutamate receptor 2Metabotropic glutamate receptor 3Negative allosteric modulator (NAM)mGlu(2) receptormGlu(3) receptor

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