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Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
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Related Experiment Video

Updated: Apr 30, 2026

Applying Hyperspectral Reflectance Imaging to Investigate the Palettes and the Techniques of Painters
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Applying Hyperspectral Reflectance Imaging to Investigate the Palettes and the Techniques of Painters

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Revealing rembrandt.

Andrew J Parker1

  • 1Department of Physiology, Anatomy and Genetics, University of Oxford Oxford, UK.

Frontiers in Neuroscience
|May 6, 2014
PubMed
Summary

Neuroscience research reveals that appreciating artwork, like Rembrandt

Area of Science:

  • Neuroaesthetics
  • Cognitive Neuroscience
  • Art Appreciation

Background:

  • Artwork significantly influences human cognition.
  • Neuroscience should integrate with, not replace, other knowledge forms.
  • Understanding art's impact on the brain is crucial.

Purpose of the Study:

  • To investigate the neural basis of artwork appreciation.
  • To explore the continuity between viewing art and general cognitive activities.
  • To examine the role of brain regions in perceiving art's authenticity.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) was employed.
  • Participants viewed artworks, including intimate portraits.
  • Brain activity was analyzed during art viewing.
Keywords:
Rembrandtartauthenticitycortical response propertiesfMRI

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Main Results:

  • Viewing artwork engages cognitive processes similar to other activities.
  • Appreciation of artwork authenticity relies on integrated visual and decision-making brain networks.
  • Intimate artworks like Rembrandt's portraits evoked significant viewer responses despite the fMRI setting.

Conclusions:

  • Neuroscientific studies can illuminate diverse cognitive responses to art.
  • Context and external factors influence how individuals perceive and respond to artwork.
  • The study highlights the brain's complex engagement with artistic stimuli.