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Secondary structure prediction for RNA binding domain in RNP proteins identifies beta alpha beta as the main
A Ghetti1, C Padovani, G Di Cesare
1Istituto di Scienze Biologiche, Università di Verona, Italy.
FEBS Letters
|November 6, 1989
Abstract:
In eukaryotic cells transcript processing is strictly dependent upon binding of specific proteins. Nuclear RNA binding proteins share a common domain, which is involved in RNA binding. In order to characterize RNP-RNA interactions we have performed a secondary structure prediction based both on statistical algorithms and comparative analysis of different proteins. A high conservation for secondary structure propensity between different RNPs was observed.