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Updated: Apr 30, 2026

Refined CLARITY-Based Tissue Clearing for Three-Dimensional Fibroblast Organization in Healthy and Injured Mouse Hearts
Published on: May 16, 2021
Double papillary fibroelastoma: beautiful, innocent flowers in the left heart
Mariana Floria1, Marina Gerard, Yves Louagie
1CHU Mont-Godinne, Université Catholique de Louvain, 1 Avenue Gaston Therasse, 5530, Yvoir, Belgium; III Medical Clinic, Sf. Spiridon University Hospital, and Gr. T. Popa University of Medicine and Pharmacy, Iasi, Romania.
Abstract:
Papillary fibroelastoma is a rare, benign tumor, and multiple papillary fibroelastomas are even more uncommon. In an asymptomatic patient scheduled for carotid endarterectomy, transthoracic echocardiography discovered a fibroelastoma on the mitral valve. Then, transesophageal echocardiography showed another fibroelastoma on the aortic valve. Because he also needed a right coronary artery bypass, the patient underwent surgical excision of both masses. Fibroelastomas are not always as innocent as they seem, and surgical excision is necessary because of their potential for systemic or coronary embolization. Transoesophageal echocardiography may improve the diagnosis of multiple papillary fibroelastomas.
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