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Severe blastomycosis in infants

Lorine Pelly1, Alaa Al Juaid, Sergio Fanella

  • 1From the *Section of Pediatric Infectious Diseases, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada; and †Pediatric Infectious Diseases, King Abdulaziz Medical City, Jeddah, Saudi Arabia.

The Pediatric Infectious Disease Journal
|May 7, 2014
PubMed

Insights

Severe blastomycosis, a fungal infection, is rare but serious in infants. This study details a severe infant case and reviews similar pediatric cases, highlighting the need for awareness in endemic regions.

Area of Science:

  • Mycology
  • Pediatric Infectious Diseases

Background:

  • Blastomycosis is a systemic fungal infection caused by the dimorphic fungus *Blastomyces dermatitidis*.
  • It typically presents as pulmonary or extrapulmonary disease in adults.
  • Infant infections are exceptionally rare, even in areas where the fungus is endemic.

Observation:

  • This report details a severe case of blastomycosis in a 4-month-old infant.
  • Two additional infant cases from the same center are also presented.
  • A review of existing literature on infant blastomycosis is included.

Findings:

  • The case series demonstrates that severe blastomycosis can occur in infants.
  • Infants may present with disseminated disease, challenging early diagnosis.
  • Early recognition and treatment are crucial for favorable outcomes in pediatric blastomycosis.

Implications:

  • Clinicians in endemic areas should consider blastomycosis in the differential diagnosis of severe illness in infants.
  • Increased awareness and further research are needed to understand pediatric blastomycosis.
  • Prompt diagnosis and management can improve outcomes for affected infants.

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